In 1991 graduated from M. V. Lomonosov Moscow State University, in 2001 — from Moscow Academy of Business under the Government of Moscow.
1991 — 1992 — Legal Adviser, Ares-ltd ТОО, Moscow.
1992 — 1993 — Lawyer, Mercury K Trade House ТОО, Moscow.
1993 — 1992 — Lawyer, Ares-ltd ТОО, Moscow.
1995 — 2002 — Legal Adviser, Edikt Legal Bureau ООО, Moscow.
2002 — 2003 — Director General, VIKS Health and Leisure Centre OOO, Korolyev, Moscow Oblast.
2003 — 2004 — Deputy Director General on Legal Affairs, Control-Service ООО, Korolyev, Moscow Oblast.
2004 — 2008 — Chief of the Division for Governance of Entrepreneurial Business, Competition and Advertising of the State Governance Department of the Ministry of Economic Development and Trade of the Russian Federation.
2008 — 2009 — Chief of the Division for Governance of Entrepreneurial Business of the State Governance Department of the Ministry of Economic Development of the Russian Federation.
2009 — 2010 — Deputy Head of the Department of Small and Medium Business of the Ministry of Economic Development of the Russian Federation.
Since December 2010 — Head of the Department of Small and Medium Business of the Ministry of Economic Development of the Russian Federation.
Natalia Larionova has got Commendation of the Minister (2006), Certificate of Honour of the Ministry of Economic Development of the Russian Federation (2007) and Commendation of the Minister (2008).